I am running the DynaBeads in my F250 with 35x12.50r18. With the big meaty tires and 4 of them to boot, I don't really notice anything as the beads are redistributing themselves coming up to 30 mph or so, but hoping they help out long term on tire wear and not throwing weights every time I leave the tire shop.
I have heard back and forth on using them on bike tires, with my lean of just getting the wheel weights that way you don't have any transitional vibrations. One thing to wonder about with bikes is the added weight on a fast or tight turn or vibration/balance when trying to do evasive manuevers.
My experience installing those little buggers...well I'll try to keep my language polite haha. They didn't like going through the valve stem, stuck together with static or would clog up causing me to have to tap on everything or pull the hose to try to get flow again. I read tips on using compressed air to "blow" them in and a few other things. End up using a vibratory device to ease things along haha. My overall recommendation on installation is to put them in while mounting the tire. Also keep in mind that you will need a filtered schrader valve so that they won't get stuck in the valve stem and cause a slow leak or not allow air back in.
If you do some Googles, some people use airsoft beads. soft and fairly durable, larger sized so won't get stuck in your valve stem. However they won't fit through your valve stem, so install when mounting. Also saw a few others that put sand in the tire.